(DNA Labeling Reagent, DLR)
Biotin-11-dXTP Analog
(DNA Labeling Reagent, DLR)
Biotin labeled-deoxynucleotide used for DNA labeling
Molecular Formula:
C24H40Li4N5O16P3S
Molecular Weight:
807.35
Purity: >95%
Concentration: 10 mM
Appearance: clear, colorless liquid
DNA Labeling Reagent, DLR, is a proprietary biotin-labeled, abasic, deoxynucleotide analog designed for efficient 3’ end-labeling of DNA using Terminal Deoxynucleotidyl Transferase (TdT) after amplification reactions such as PCR. When used with streptadivin conjugated to a reporter, the 3’ biotin labeled DNA fragment can be detected by enzyme activity, fluorescence, or by the binding of a secondary antibody. In addition, DLR will not base-pair with natural nucleotides, thus reducing non-specific binding and maximizing the signal-to-noise ratio. DLR is a component of the Affymetrix GeneChip DNA labeling reagent (product # 900542) and has been used extensively to successfully probe microarrays for decades.
