n-Octyl-β-D-Glucopyranoside, Sol-Grade
n-Octyl-β-D-Glucoside
O311S: Purity >97% (HPLC); alpha isomer <5%, a dialyzable nonionic detergent for functional solubilization and purification of membrane protein
Molecular Formula:
C14H28O6
Molecular Weight:
292.4
CMC (H2O): ~ 18-20 mM(1) (0.53%)
CMC (0.1 M NaCl): ~ 23.4 mM(2)
Aggregation Number (H2O)(1): ~ 27-100
dn/dc (H2O)(7): 0.1159 mL/gm
Purity: ≥ 97% pure by HPLC analysis.
Percent alpha: < 5 (HPLC)
Percent octanol: < 0.05 (HPLC)
pH (1% solution): 4-9
Solubility in water at 20°C: ≥ 20%
Conductance (10% solution): < 500 μS
Absorbance of a 1% detergent solution:
340 nm: < 0.05
280 nm: < 0.1
260 nm: < 0.1
225 nm: < 0.2
1. Lorber, B., Bishop, J. B. and DeLucas, L. J. (1990) Biochim. Biophys. Acta 1023, 254-265.
2. Chattopadhyay, A. and London, E. (1984) Anal. Biochem. 139, 408-412.
3. Womack, M. D., Kendall, D. A. and MacDonald, R. C. (1983) Biochim. Biophys. Acta 733, 210-215.
4. Brown, G. M., Dubreuil, P., Ichhaporia, F. M. and Desnoyers, J. E. (1970) Canadian J. Chem. 48, 2525-2531.
5. Conlan, S. and Bayley, H. (2003) Biochem. 42, 9453-9465.
6. Fanucci, G. E., Lee, J. Y., and Cafiso, D. S. (2003) Biochemistry 42, 13106-13112.
7. Measurement obtained in collaboration with Professor Mark Foster (University of Akron) under an experimental services contract
CAS:
29836-26-8
